![]() Toxic megacolon may be fatal and requires emergency surgery. Bacteria from the colon may then enter your abdominal cavity or bloodstream. In this rare condition, your colon is unable to expel gas and stool, causing it to become greatly enlarged (megacolon). In some cases, dehydration can occur so quickly that kidney function rapidly deteriorates (kidney failure). ![]() This makes it difficult for your body to function normally and can cause blood pressure to drop to dangerously low levels. Severe diarrhea can lead to a significant loss of fluids and electrolytes. difficile infection, for reasons that are not clearly understood. Women are more likely than men to have C. difficile infection increases your chance of having another one, and the risk continues to increase with each infection. difficile was 10 times greater for people age 65 and older compared with younger people. In one study, the risk of becoming infected with C. Weakened immune system from a medical condition or treatment (such as chemotherapy).Having a serious illness or medical procedureĬertain medical conditions or procedures may make you more susceptible to a C. Stethoscopes, thermometers or other devices.difficile infections occur in people who are or who have recently been in a health care setting - including hospitals, nursing homes and long-term care facilities - where germs spread easily, antibiotic use is common and people are especially vulnerable to infection. Proton pump inhibitors, a type of medicine used to reduce stomach acid, also may increase your risk of C. While any antibiotic can be implicated, the antibiotics that most often lead to C. difficile can quickly grow out of control. Without enough helpful bacteria to keep it in check, C. When you take antibiotics to treat an infection, these drugs tend to destroy some of the helpful bacteria in your body in addition to the bacteria causing the infection. Your intestines contain about 100 trillion bacterial cells and between 500 to 2,000 different kinds of bacteria, many of which help protect your body from infection. ![]() difficile, certain factors increase the risk. Risk factorsĪlthough people who have no known risk factors have gotten sick from C. difficile to survive outside the body enables the generally easy transmission of the bacterium, particularly in the absence of thorough hand-washing and cleaning. When bacteria once again find their way into a person's digestive system, they "wake up" and can begin to produce infection again. This enables them to survive for a long time in any number of places: When the bacteria are outside the colon - virtually anywhere in the environment - they are in a dormant state, or essentially shutdown. These toxins destroy cells, produce patches of inflammatory cells and cellular debris, and cause watery diarrhea. When they reach the large intestine (colon), they can release tissue-damaging toxins. They can begin reproducing in the small intestine. difficile bacteria enter the body through the mouth. The rectum makes up the last several inches of the colon.Ĭ. The colon carries waste to be expelled from the body. It's the longest part of the large intestine. The colon is a long tubelike organ in the abdomen. Some people have loose stools during or shortly after antibiotic therapy. People who have these conditions are admitted to the intensive care unit. Sepsis is a life-threatening condition that occurs when the body's response to an infection damages its own tissues. difficile infection that is severe and sudden, an uncommon condition, may also cause intestinal inflammation leading to enlargement of the colon (also called toxic megacolon) and sepsis.
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